Constantinou Lab Publications: Biomedical Engineering
Peng Q, Jones RC & Constantinou CE. Application Of 2d Ultrasound Image Processing In Identifying The Dynamic Response of The Urogenital Structures to Voluntary and Reflex Pelvic Floor Contractions Annals of Biomedical Engineering. (In press 2006)
Murayama Y, Constantinou CE, Omata S. Remote sensing of mechanical properties of materials using a novel ultrasound transducer and signal processing.IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar;52(3):439-44. [view pdf]
Omata S, Murayama Y, Constantinou CE. Multi-sensory surgical support system incorporating, tactile, visual and auditory perception modalities. Stud Health Technol Inform. 2005;111:369-71. [view pdf]
Omata S, Murayama Y, Constantinou CE. Development of a novel surgical support instrument and virtual system incorporating new tactile sensor technology. Stud Health Technol Inform. 2004;98:288-90.
Tillig B, Mutschke O, Rolle U, Gaunitz U, Asmussen G, Constantinou CE. Effects of artificial obstruction on the function of the upper urinary tract of Guinea pigs, rats and pigs. Eur J Pediatr Surg. 2004 Oct;14(5):303-15.
Yokota T, Honda K, Tsuruya Y, Nomiya M, Yamaguchi O, Gotanda K, Constantinou CE. Functional and anatomical effects of hormonally induced experimental prostate growth: a urodynamic model of benign prostatic hyperplasia (BPH) in the beagle. Prostate. 2004 Feb 1;58(2):156-63. [view pdf]
Murayama Y, Constantinou CE, Omata S. Micro-mechanical sensing platform for the characterization of the elastic properties of the ovum via uniaxial measurement. J Biomech. 2004 Jan;37(1):67-72. [view pdf]
Schmidt F, Yoshimura Y, Shin PY, Constantinou CE. Comparative urodynamic patterns of bladder pressure, contractility and urine flow in man and rat during micturition. APMIS Suppl. 2003;(109):39-44.
Yoshimura Y, Yamaguchi O, Bellamy F, Constantinou CE. Effect of Pygeum africanum tadenan on micturition and prostate growth of the rat secondary to coadministered treatment and post-treatment with dihydrotestosterone. Urology. 2003 Feb;61(2):474-8. [view pdf]
Tillig B, Constantinou CE. Supraspinal N-methyl-D-aspartate receptor inhibition influences the micturition reflex and function of the upper urinary tract of anesthetized and conscious rats. Neurourol Urodyn. 2003;22(2):164-75. [view pdf]
Constantinou CE, Damaser MS, Perkash I. Displacement sequence and elastic properties of anterior prostate/urethral interface during micturition of spinal cord injured men. Ultrasound Med Biol. 2002 Sep;28(9):1157-63. [view pdf]
Schmidt F, Shin P, Jorgensen TM, Djurhuus JC, Constantinou CE. Urodynamic patterns of normal male micturition: influence of water consumption on urine production and detrusor function. J Urol. 2002 Oct;168(4 Pt 1):1458-63.
[view pdf]
Constantinou CE, Hvistendahl G, Ryhammer A, Nagel LL, Djurhuus JC. Determining the displacement of the pelvic floor and pelvic organs during voluntary contractions using magnetic resonance imaging in younger and older women. BJU Int. 2002 Sep;90(4):408-14. [view pdf]
Schmidt F, Yoshimura Y, Ni RX, Kneesel S, Constantinou CE. Influence of gender on the diurnal variation of urine production and micturition characteristics of the rat. Neurourol Urodyn. 2001;20(3):287-95. [view pdf]
Yoshimura Y, Schmidt F, Constantinou CE. Gender specificity of tolterodine on micturition and the diurnal variation of urine production of the conscious rat. BJU Int. 2000 Nov;86(7):879-85. [view pdf]
Choo MS, Bellamy F, Constantinou CE. Functional evaluation of Tadenan on micturition and experimental prostate growth induced with exogenous dihydrotestosterone. Urology. 2000 Feb;55(2):292-8. [view pdf]
Diep N, Constantinou CE. Age dependent response to exogenous estrogen on micturition, contractility and cholinergic receptors of the rat bladder. Life Sci. 1999;64(23):PL 279-89. [view pdf]
Lee JZ, Tillig B, Perkash I, Constantinou CE. Effect of alpha1 adrenoceptor antagonist on the urodynamics of the upper and lower urinary tract of the male rat. Neurourol Urodyn. 1998;17(3):213-29. [view pdf]
Lee JZ, Omata S, Tillig B, Perkash I, Constantinou CE. Chronology and urodynamic characterization of micturition in neurohormonally induced experimental prostate growth in the rat. Neurourol Urodyn. 1998;17(1):55-69. [view pdf]
Watanabe T, Omata S, Lee JZ, Constantinou CE. Comparative analysis of bladder wall compliance based on cystometry and biosensor measurements during the micturition cycle of the rat. Neurourol Urodyn. 1997;16(6):567-81. [view pdf]
Watanabe T, Perkash I, Constantinou CE. Modulation of detrusor contraction strength and micturition characteristics by intrathecal baclofen in anesthetized rats. J Urol. 1997 Jun;157(6):2361-5. [view pdf]
Tillig B, Constantinou CE. Videomicroscopic imaging of ureteral peristaltic function in rats during cystometry. J Pharmacol Toxicol Methods. 1996 Aug;35(4):191-202. [view pdf]
Constantinou CE. Influence of hormone treatment on prostate growth and micturition characteristics of the rat. Prostate. 1996 Jul;29(1):30-5. [view pdf]
Watanabe T, Constantinou CE. Analysis of pressure/flow characteristics in the female rat and their pharmacologic modulation. Neurourol Urodyn. 1996;15(5):513-27.
Constantinou CE, Omata S. Analysis of the relative biomechanical effects of alpha 1 and alpha 2 antagonists in modifying the compliance of the prostate and micturition parameters of the hormonally manipulated male rat. Neurourol Urodyn. 1996;15(1):85-101.
Hatzichristou DG, Omata S, Constantinou CE. New method for direct stiffness measurement of the corpora cavernosa. Int J Impot Res. 1995 Dec;7(4):221-31.
Sadao O, Constantinou CE. Modeling of micturition characteristics based on prostatic stiffness modulation induced using hormones and adrenergic antagonists. IEEE Trans Biomed Eng. 1995 Aug;42(8):843-8.
Christensen LL, Djurhuus JC, Constantinou CE. Imaging of pelvic floor contractions using MRI. Neurourol Urodyn. 1995;14(3):209-16.
Lui PD, Terris MK, Haney DJ, Constantinou CE, Stamey TA. Prostate specific antigen as a predictor of an abnormal digital rectal examination. Br J Urol. 1994 Sep;74(3):337-40.
Harada T, Constantinou CE. The effect of alpha 2 agonists and antagonists on the lower urinary tract of the rat. J Urol. 1993 Jan;149(1):159-64.
Constantinou CE, Freiha FS. Impact of radical prostatectomy on the characteristics of bladder and urethra. J Urol. 1992 Oct;148(4):1215-9; discussion 1219-20. [view pdf]
Issa MM, Shortliffe LM, Constantinou CE. The effect of bacteriuria on bladder and renal pelvic pressures in the rat. J Urol. 1992 Aug;148(2 Pt 2):559-63; discussion 564-5.
Harada T, Levounis P, Constantinou CE. Rapid evaluation of the efficacy of pharmacologic agents and their analogs in enhancing bladder capacity and reducing the voiding frequency.
J Pharmacol Toxicol Methods. 1992 Apr;27(2):119-26. Constantinou CE. Pharmacologic treatment of detrusor incontinence with thiphenamil HCl. Urol Int. 1992;48(1):42-7.
Constantinou CE. Relaxant effect of thiphenamil HCl on upper urinary tract frequency of contraction of healthy asymptomatic volunteers. Urol Int. 1992;48(1):35-8.
Constantinou CE. Pharmacologic effect of thiphenamil HCl on lower urinary tract function of healthy asymptomatic volunteers. Urol Int. 1992;48(3):293-8.
Harada T, Constantinou CE. Renal pelvic pressure isolation from active and passive bladder pressures in the rat: the facilitating effect of urine flow rate. Urol Int. 1992;48(3):284-92.
Potjer RM, Kimoto Y, Constantinou CE. Topological localization of the frequency and amplitude characteristics of the whole and segmented renal pelvis. Urol Int. 1992;48(3):278-83.
Kimoto Y, Kumazawa J, Kessler R, Constantinou CE. Relaxation mechanisms of antispasmodics papaverine and thiphenamil on the human corpus cavernosum. Jpn J Pharmacol. 1992;58 Suppl 2:384P.
Kimoto Y, Kumazawa J, Kessler R, Constantinou CE. Endothelium dependent relaxation of human corpus cavernosum by bradykinin. Jpn J Pharmacol. 1992;58 Suppl 2:321P.
Sorensen S, Waechter PB, Constantinou CE, Kirkeby HJ, Jonler M,Djurhuus JC. Urethral pressure and pressure variations in healthy fertile and postmenopausal women with reference to the female sex hormones. J Urol. 1991 Nov;146(5):1434-40.
Smyth TB, Shortliffe LM, Constantinou CE. The effect of urinary flow and bladder fullness on renal pelvic pressure in a rat model. J Urol. 1991 Aug;146(2 ( Pt 2)):592-6.
Kimoto Y, Constantinou CE. Regional effects of indomethacin, acetylsalicylic acid and SC-19220 on the contractility of rabbit renal pelvis (pacemaker regions and pelviureteric junction. J Urol. 1991 Aug;146(2):433-8.
Prionas SD, Raftery KA, Edmonds PD, Constantinou CE. Flow dependence of 2-D temperature distributions induced in the perfused canine kidney by ultrasound. Int J Hyperthermia. 1991 Mar-Apr;7(2):367-83.
Kimoto Y, Kessler R, Constantinou CE. Relaxation mechanisms of antispasmodics papaverine and thiphenamil on the human corpus cavernosum. J Urol. 1990 Dec;144(6):1497-9.
Kimoto Y, Kessler R, Constantinou CE. Endothelium dependent relaxation of human corpus cavernosum by bradykinin. J Urol. 1990 Oct;144(4):1015-7.
Djurhuus JC, Frokjaer J, Munch Jorgensen T, Knudsen L, Pham T, Constantinou CE. Regulation of renal pelvic pressure by diuresis and micturition. Am J Physiol. 1990 Sep;259(3 Pt 2):R637-44.
Kimoto Y, Constantinou CE. Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis. Eur J Pharmacol. 1990 Jan 17;175(3):359-62.
Yamaguchi OA, Constantinou CE. Renal calyceal and pelvic contraction rhythms. Am J Physiol. 1989 Oct;257(4 Pt 2):R788-95.
Potjer RM, Constantinou CE. Frequency of spontaneous contractions in longitudinal and transverse bladder strips. Am J Physiol. 1989 Oct;257(4 Pt 2):R781-7.
Shortliffe LM, Freiha FS, Kessler R, Stamey TA, Constantinou CE. Treatment of urinary incontinence by the periurethral implantation of glutaraldehyde cross-linked collagen. J Urol. 1989 Mar;141(3):538-41.
Harris RG, Constantinou CE, Stamey TA. Extravesical subtrigonal injection of 50 per cent ethanol for detrusor instability. J Urol. 1988 Jul;140(1):111-6.
Levounis P, Constantinou CE. Analysis of the in vitro pharmacologic response of renal pelvis and detrusor smooth muscle to thiphenamil, oxybutynin and verapamil. Urol Int. 1988;43(4):211-8.
Griffiths DJ, Constantinou CE, Mortensen J, Djurhuus JC. Dynamics of the upper urinary tract: II. The effect of variations of peristaltic frequency and bladder pressure on pyeloureteral pressure/flow relations. Phys Med Biol. 1987 Jul;32(7):823-33.
Kessler R, Constantinou CE. Internal urethrotomy in girls and its impact on the urethral intrinsic and extrinsic continence mechanisms. J Urol. 1986 Dec;136(6):1248-53. [view pdf]
Griffiths DJ, Constantinou CE, van Mastrigt R. Urinary bladder function and its control in healthy females. Am J Physiol. 1986 Aug;251(2 Pt 2):R225-30.
Vercesi LA, Constantinou CE. Pressure evaluation of the antireflux ability of the rat ureterovesical junction. Urol Int. 1986;41(3):192-5.
Constantinou CE. Determinants of cure by endoscopic suspension of the bladder neck in the incontinent female patient. World J Urol. 1986;4:10-15. [view pdf]
Constantinou CE. Resting and stress urethral pressures as a clinical guide to the mechanism of continence. Clin Obstet Gynaecol. 1985 Jun;12(2):343-56.
Constantinou CE. Resting and stress urethral pressures as a clinical guide to the mechanism of continence in the female patient. Urol Clin North Am. 1985 May;12(2):247-58.
Constantinou CE, Djurhuus JC, Silverman DE, Towns AB, Wong L, Govan DE. Isometric detrusor pressure during bladder filling and its dependency on bladder volume and interruption to flow in control subjects. J Urol. 1984 Jan;131(1):86-90.
Constantinou CE, Govan DE. Spatial distribution and timing of transmitted and reflexly generated urethral pressures in healthy women. J Urol. 1982 May;127(5):964-9. [view pdf]
Constantinou CE. Principles and methods of clinical urodynamic investigations. Crit Rev Biomed Eng. 1982 Mar;7(3):229-64.
Djurhuus JC, Constantinou CE. Chronic ureteric obstruction and its impact on the coordinating mechanisms of peristalsis (pyeloureteric pacemaker system). Urol Res. 1982;10(6):267-70.
Constantinou CE, Yamaguchi O. Multiple-coupled pacemaker system in renal pelvis of the unicalyceal kidney. Am J Physiol. 1981 Nov;241(5):R412-8.
Constantinou CE, Djurhuus JC. Pyeloureteral dynamics in the intact and chronically obstructed multicalyceal kidney. Am J Physiol. 1981 Nov;241(5):R398-411.
Del Tacca M, Constantinou CE, Bernardini C. The effects of drugs on pacemaker regions of isolated rabbit renal pelvis. Eur J Pharmacol. 1981 Apr 24;71(1):43-51.
Constantinou CE. Urodynamics of the pyeloureteral system. Prog Clin Biol Res. 1981;78:389-92.
Shugart-Reimnitz C, Constantinou CE. Gradient of total [Ca++] in the renal pelvis. Urol Int. 1981;36(4):256-64.
Reimnitz J, Shugart-Reimnitz C, Tung H, Constantinou CE. Total [Na+] and [K+] gradient in the pyeloureter. Urol Int. 1981;36(4):235-44.
Constantinou CE, Faysal MH, Rother L, Govan DE. The impact of bladder neck suspension on the mode of distribution of abdominal pressure along the female urethra. Prog Clin Biol Res. 1981;78:121-32.
Constantinou CE, Govan DE. Contribution and timing of transmitted and generated pressure components in the female urethra. Prog Clin Biol Res. 1981;78:113-20.
Faysal MH, Constantinou CE, Rother LF, Govan DE. The impact of bladder neck suspension on the resting and stress urethral pressure profile: a prospective study comparing controls with incontinent patients preoperatively and postoperatively. J Urol. 1981 Jan;125(1):55-60.
Mensah-Dwumah M, Djurhuus JC, Constantinou CE. Hydronephrotic alterations in calyceal and renal pelvic pacemaker function of the in vitro pyeloureteral system. Urol Int. 1980;35(3):161-6.
Constantinou CE, Govan DE. Urodynamic analysis of urethral, vesical and perivesical pressure distribution in the healthy female. Urol Int. 1980;35(1):63-72. [view pdf]
Djurhuus JC, Constantinou CE. Assessment of pyeloureteral function using a flow velocity and cross-sectional diameter probe. Invest Urol. 1979 Sep;17(2):103-7.
Constantinou CE. Velocity gradient and contraction frequency of the pyeloureteral system. Experientia. 1979 Jun 15;35(6):791-2.
Constantinou CE, Neubarth JL, Mensah-Dwumah M. Frequency gradient in the autorhythmicity of the pyeloureteral pacemaker system. Experientia. 1978 May 15;34(5):614-5.
Constantinou CE. Contractility of the pyeloureteral pacemaker system. Urol Int. 1978;33(6):399-416.
Constantinou CE, Silvert MA, Gosling J. Pacemaker system in the control of ureteral peristaltic rate in the multicalyceal kidney of the pig. Invest Urol. 1977 May;14(6):440-1.
Constantinou CE, Hrynczuk JR. Urodynamics of the upper urinary tract. Invest Urol. 1976 Nov;14(3):233-40.
Gosling JA, Constantinou CE. The origin and propagation of upper urinary tract contraction waves. A new in vitro methodology. Experientia. 1976 Feb 15;32(2):266-7.
Constantinou CE, Hrynczuk JR. Renal pelivic pacemaker arrhythmias induced by pentothal anesthesia. Urol Int. 1976;31(6):489-500.
Constantinou CE, Hrynczuk JR. The incidence of ecotpic peristaltic contractions. Urol Int. 1976;31(6):476-88.
Zawalinski VC, Constantinou CE, Burnstock G. Ureteral pacemaker potentials recorded with the sucrose gap technique. Experientia. 1975 Aug 15;31(8):931-3.
Constantinou CE. Statistical properties of the temporal and spatial distribution of interperistaltic intervals and their relationship to pacemaker and respiratory rhythmicity. Urol Int. 1975;30(5):369-80.
Constantinou CE. Renal pelvic pacemaker control of ureteral peristaltic rate. Am J Physiol. 1974 Jun;226(6):1413-9.
Constantinou CE, Tsuchida S, Kavaney PB, Hayman WP, Govan DE. Simulated vesicoureteral reflux: comparison between the normal and hydrostatically bypassed ureterovesical junction as a function of urine flow rate and bladder pressure. Urol Int. 1974;29(4):265-79.
Constantinou CE, Granato JJ Jr, Govan DE. Dynamics of the upper urinary tract: accommodations in the rate and stroke volume of ureteral peristalsis as a response to transient alteration in urine flow rate. Urol Int. 1974;29(4):249-64.
Constantinou CE, Granato JJ Jr, Govan DE. Effects of radiopaque contrast media on the dynamic characteristics of ureteral function. Urol Int. 1974;29(6):401-13.
Briggs EM, Constantinou CE, Govan DE. Dynamics of the upper urinary tract. The relationship of urine flow rate and rate of ureteral peristalsis. Invest Urol. 1972 Jul;10(1):56-62.
Sands JP, Constantinou CE, Govan DE. Bladder pressure and its effect on mean arterial blood pressure. Invest Urol. 1972 Jul;10(1):14-8.
Rosen DI, Constantinou CE, Sands JP, Govan DE. Dynamics of the upper urinary tract: effects of changes in bladder pressure on ureteral peristalsis. J Urol. 1971 Aug;106(2):209-13.
Dale RL, Constantinou CE, Briggs EM, Govan DE. Dynamics of the upper urinary tract. The effects of an indwelling ureteral catheter on ureteral peristalsis. Invest Urol. 1971 May;8(6):655-72.
Constantinou CE, Dale RL, Briggs EM, Perkash I, Engelsgjerd GL, Govan DE. Dynamics of the upper urinary tract. System for data collection and evaluation. Invest Urol. 1971 May;8(6):645-54.
Constantinou CE, Briggs EM. Precision electrostatic urine flowmeter. J Appl Physiol. 1970 Sep;29(3):396-7.
